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Posted by Brian on 6th March 2010 at 04:00 PM
New Discovery to Pave Way for New Class of AIDS Drug
A team of researchers at the renowned Scripps Research Institute has discovered two new compounds that prove the existence of new binding sites on HIV protease.

According to the World Health Organization, about 33 million people currently live with HIV infections. Several drugs used to treat AIDS inhibit this HIV protease target, but drug-resistant mutants that impede the effectiveness of these drugs keep appearing and getting worse. Utilizing computing power from 1.5 million devices networked through IBM's World Community Grid, the new sites on the HIV protease are being used as docking targets for virtual screening experiments, in order to guide the development of these chemical compounds into a new class of potent HIV inhibitors.



IBM World Community Grid Announcement with Scripps Research Institute

Shotlist:
Exterior Scripps Research Institute

Animation of AIDS Virus

Dr. Olson at computer, Scripps

Worker in Scripps lab

Models of HIV virus

HIV virus on screen

CU HIV model

Worker in Scripps lab

HIV/AIDS graphic

Int. Dr. Olson, Scripps

Person at computer

WCG graphic

WCG web site

People at computer

Dr. Jasinski int., IBM

Animation of HIV/AIDS virus

Person at computer

Animation of HIV/AIDS virus

Worker in lab

US Capital

Lab shots

WCG web site

Person at computer

Fight AIDS@Home graphic

Dr. Olson int.

WCG graphic

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